NFL schedule has finally been released! Check out our game-by-game predictions for every Lions game of the regular season.

Iyer picked the top game for all 32 teams' 2025 schedule and wrote that the Rams' matchups against the Detroit Lions in Week 15, the San Francisco 49ers in Weeks 5 and 10, and Atlanta Falcons in Week 17 will be those respective club's best games of their individual seasons.

The Lions have five prime-time games, one less than the max allowed (leaving room in case Week 18 needs a primetime flex, a la in 2024). In total, 12 of their games are on national television, and that’s not including Week 18, which does not have a scheduled time or network yet.

With the NFL releasing the 2025 regular season schedule on Wednesday, this year's Thanksgiving slate has officially been announced. The NFL will continue holding three games on Thanksgiving, with the Detroit Lions and Dallas Cowboys each hosting a game, as is tradition.